Appointed the first woman, Ellen Louks Fairclough, and the first Canadian of Ukrainian origin, Michael Starr, to Cabinet on June 21, 1957.
Recommended the appointment of the first North American Indian, James Gladstone, to the Senate as of January 31, 1958.
Recommended the appointment of the first French Canadian, Major General Georges Philias Vanier, as Governor General as of August 1, 1959.
The John Diefenbaker Defender of Human Rights and Freedom Award is created in his honour, February 8, 2012.